Scaffold attachment factor b2
WebThe protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix … WebNov 26, 2024 · The location of a scaffold will make a big difference in whether or not it needs to be secured to a building. The type of ground the scaffolding rests on, the …
Scaffold attachment factor b2
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WebAlternative RNA splicing complexes containing the scaffold attachment factor SAFB2. Biological context of SAFB2 Scaffold attachment factor B1 ( SAFB1 ) and SAFB2 are large, multifunctional proteins that have been implicated in numerous cellular processes including chromatin organization, transcriptional regulation, RNA splicing , and stress ... WebThe scaffold attachment factor SAFB2, a component of high molecular weight nuclear protein complexes which contains a core set of protein interaction partners, functions as an estrogen receptor corepressor. It directly interacts with ER alpha repressing transcription via repression domains. Its overexpression results in inhibition of proliferation.
WebMay 30, 2003 · We have characterized previously the nuclear matrix protein/scaffold attachment factor (SAFB) as an estrogen receptor corepressor and as a potential tumor … WebScaffold attachment factor B2is a proteinthat in humans is encoded by the SAFB2gene. [5][6] Interactions SAFB2 has been shown to interactwith Estrogen receptor alpha[5]and …
WebDec 29, 2024 · The family of scaffold attachment factor B (SAFB) proteins comprises three members and was first identified as binders of the nuclear matrix/scaffold. Over the past two decades, SAFBs were shown to act in DNA repair, mRNA/ (l)ncRNA processing, and as part of protein complexes with chromatin-modifying enzymes. WebJun 18, 2015 · SAFB1 (scaffold attachment factor B1) and a second family member SAFB2, are multifunctional proteins implicated in a variety of cellular processes including cell …
WebScaffold attachment factor B, also known as SAFB, is a gene with homologs that have been studied in humans and mice. Function. This gene encodes a DNA-binding protein that has specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the ...
WebSep 1, 2015 · Scaffold attachment binding factors (SAFBs) are a family of multifunctional proteins that include SAFB2, SAFB1 and the scaffold attachment factor-like … results of 2020 pga championshipWebFeb 5, 2024 · Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα. Hashimoto T, Matsuda K, Kawata MHashimoto … prtg training and certificationWebThe National Library of Medicine (NLM), on the NIH campus in Bethesda, Maryland, is the world's largest biomedical library and the developer of electronic information services that delivers data to millions of scientists, health professionals and members of the public around the globe, every day. results of 2021 mosconi cupWebJan 18, 2024 · Scaffold attachment factor-B2 (SAFB2) is identified as a nuclear matrix-associated protein and belongs to the family of nuclear proteins . The SAFB2 gene maps … results of 2022 high school rally ullWeb100081088 - Gene ResultLOC100081088 scaffold attachment factor B2 [ (platypus)] LOC100081088 scaffold attachment factor B2 [ (platypus)] Gene ID: 100081088, updated on 16-Apr-2024 Summary Other designations scaffold attachment factor B2, scaffold attachment factor B, scaffold attachment factor B1 prtg trend microWebJan 18, 2024 · Scaffold attachment factor-B2 (SAFB2) is identified as a nuclear matrix-associated protein and belongs to the family of nuclear proteins [ 4 ]. The SAFB2 gene maps to human chromosome 19p13.3, which localized in the nuclear matrix and has a broad expression profile in human tissues [ 5 ]. results of 2019 general electionWebBinds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation. The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is … prtg tracert